Toxicological approach of Parthenium Hysterophorus (linn.) On sperm dynamics and male fertility of rattus norvegicus

Shikha Soni; S.K. Singh

doi:10.53724/jmsg/v2n1.02

Authors

Shikha Soni Shikha Soni Department of Zoology, M.S.J. Govt. P.G. College, Bharatpur, Maharaja Surajmal Brij University, Bharatpur (Rajasthan), India https://orcid.org/0000-0001-7742-2234
S.K. Singh Lecturer (Zoology), Department of Zoology, Department of Zoology, M.S.J. Govt. P.G. College, Bharatpur, Maharaja Surajmal Brij University, Bharatpur (Rajasthan), India

DOI:

https://doi.org/10.53724/jmsg/v2n1.02

Keywords:

Parthenin, Testes, Sperm Count, Motility, Abnormality, Parthenium hysterophorus, Rattus norvegicus

Abstract

Parthenium hysterophorus Linn., an exotic plant has now dominated most of the herbaceous flora of many countries. It is a weed of national significance belongs to family Asteraceae. The compound Parthenin extracted from parthenium hysterophorus was orally administrated to Rattus norvegicus at 60.0 mg/kg b.wt. for acute and 2.o mg/kg b.wt. for sub-chronic (30 days) treatment to study its impact on testicular fertility parameters to different groups of animals. Results from the present study have elucidated that sperm parameters (Fertility index, sperm count, sperm motility and sperm abnormality) showed a marked decrease in their functioning, and toxic effects on male reproductive functions. The observed testicular changes are suggestive of testes dysfunction and additional mode of action of Parthenium leaf extract.

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